CAPÍTULO 28 - SEQUESTRO ESPLÊNICO AGUDO EM CRIANÇAS COM ANEMIA FALCIFORME

Doi: 10.58871/conbrasca.v4.28

PALAVRAS CHAVE: anemia falciforme; pediatria; criança; tratamento; esplenopatias.

KEYWORDS: sickle cell, anemia; pediatrics; child; treatment; splenic diseases.

ABSTRACT:
Sickle cell anemia is one of the most prevalent genetic conditions in Brazil and worldwide. It involves a complex pathophysiology that includes a physicochemical alteration of hemoglobin, which can lead to sickling and vaso-occlusion, triggering acute clinical manifestations with high morbidity and mortality, such as splenic sequestration. The objective is to offer a comprehensive analysis of this complication, emphasizing its relevance in managing sickle cell anemia, as well as identifying optimized treatments for the condition. The methodology employed is a narrative review, utilizing databases such as LILACS, PUBMED, BVS, and MEDLINE, with the descriptors Sickle Cell Anemia AND Splenic Diseases AND Treatment AND Child OR Pediatrics. Results and discussion reveal it as a condition with high morbidity and mortality, acutely diagnosed by spleen enlargement and abrupt hemoglobin drop. Regarding treatment, there' s a debate between conservative and surgical approaches, without an established consensus. Final considerations highlight a lack of studies in the literature for more effective outcome-modifying strategies.

Autor

  • ALLAN VITOR PRAZERES MELO

  • ANA RITA MENDES CORREA

  • BEATRIZ DE PAULA DEL PUPO BARROS

  • CARLOS ALBERTO SIQUEIRA MENDONÇA

  • EWERTON FERNANDES LEITÃO

  • FILIPE LUCENA DA SILVA QUEIROZ

  • GABRIEL ACIOLY DE OMENA BENTO

  • GABRIELA DE ALMEIDA CAVALCANTE

  • MARIA ALEXSANDRA EUGÊNIA DA SILVA

  • MARIANA LUCENA DA SILVA QUEIROZ

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Desenvolvido por Alexsander Arcelino